Patient-centered research: how do women tolerate nipple fluid aspiration as a potential screening tool for breast cancer?

Table 1 Cohort characteristics

Cohort	All	Healthy volunteers cohort	Breast cancer cohort	High-risk cohort	P value	P value	P value
Cohort	All	Healthy volunteers cohort	Breast cancer cohort	High-risk cohort	HC vs. BC	BC vs. HR	HC vs. HR
n	375	190	137	48
Age, median (Q25-Q75)	54 (47–62)	54 (49–60)	56 (49.5–67.5)	36 (27–48)	0.093	< 0.001	< 0.001
Mammography, n	319	154 (81%)	137(100%)	31 (62%)	< 0.001	< 0.001	< 0.002
Breast MRI, n	114	3 (2%)	76 (56%)	36 (72%)	< 0.001	0.034	< 0.001
Blood collection, n	358	184 (96.8%)	130 (94.9%)	44 (91.7%)	0.950	0.082	0.064
Breast physical examination, n	250	92 (48%)	112 (82%)	43 (86%)	< 0.001	0.563	< 0.001
Ever breastfed, n	254	139 (73%)	91 (66%)	27 (56%)	0.245	< 0.001	< 0.001

In the high-risk cohort, only data from the first visit was considered for this baseline table. Abbreviations: Q25-Q75 Inter-quartile range between quartile 25 and quartile 75, MRI Magnetic resonance imaging, HC Healthy volunteers cohort, BC Breast cancer cohort, HR High-risk cohort

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