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Table 2 Comparison of selected DVH parameters for locoregional lymph node levels in axillary levels I-III, supraclavicular and internal mammary region and contralateral breast in DIBH and FB technique

From: Incidental irradiation of the regional lymph nodes during deep inspiration breath-hold radiation therapy in left-sided breast cancer patients: a dosimetric analysis

DVH parameter

FB

DIBH

Change [%]

p-value

Effect size r

 

Mean value

Range

Mean value

Range

   

Axillary level I

 Volume [ccm]

62.62

17.90–126.90

62.83

16.70–119.40

0.34

0.210

0.103

 Dmean [Gy]

34.93

10.52–50.40

32.28

2.87–51.7

-7.59

 < 0.0001

0.375

 D50% [Gy]

39.02

2.75–52.05

35.42

1.64–53.35

-9.23

 < 0.0001

0.388

 Dmax [Gy]

51.4

39.71–64.12

51.27

39.10–63.95

-0.25

0.997

0

 Dmin [Gy]

3.18

0.00–44.21

2.75

0.00–43.88

-13.52

0.009

0.213

 V30 Gy [%]

68.55

14.54–100

62.22

0.5–100

-9.23

 < 0.0001

0.384

 V40 Gy [%]

52.99

0.00–100

47.09

0.00–100

-11.13

 < 0.0001

0.321

Axillary level II

 Volume [ccm]

17.98

8.10–40.40

18.21

7.55–40.60

1.28

0.062

0.153

 Dmean [Gy]

16.40

0.38–52.40

20.10

0.44–53.84

22.56

 < 0.0001

0.453

 D50% [Gy]

15.29

0.38–52.37

19.65

0.44–52.32

28.52

 < 0.0001

0.423

 Dmax [Gy]

34.54

0.58–57.94

38.80

0.69–60.11

12.33

 < 0.0001

0.376

 Dmin [Gy]

2.80

0.22–42.77

2.96

0.00–46.80

5.71

0.002

0.253

 V30 Gy [%]

28.41

0.00–100

36.33

0.00–100

27.88

 < 0.0001

0.415

 V40 Gy [%]

17.74

0.00–100

22.94

0.00–100

29.31

 < 0.0001

0.439

Axillary level III

 Volume [ccm]

8.61

4.00–19.40

8.28

3.80–20.10

-3.83

 < 0.0001

0.445

 Dmean [Gy]

3.06

0.21–40.48

3.84

0.25–39.23

25.49

 < 0.0001

0.466

 D50% [Gy]

2.38

0.21–47.19

3.23

0.25–44.97

35.71

 < 0.0001

0.463

 Dmax [Gy]

10.55

0.27–52.94

13.09

0.30–52.32

24.08

 < 0.0001

0.492

 Dmin [Gy]

0.80

0.13–3.58

0.87

0.16–3.24

8.75

 < 0.0001

0.45

 V30 Gy [%]

2.41

0.00–80.84

3.60

0.00–81.44

49.38

0.117

0.129

 V40 Gy [%]

1.35

0.00–70.92

2.16

0.00–67.69

60

0.212

0.103

Supraclavicular

 Volume [ccm]

27.16

15.16–38.50

25.97

13.02–37.30

-4.38

 < 0.0001

0.723

 Dmean [Gy]

0.84

0.22–10.80

0.82

0.23–4.11

-2.38

0.002

0.26

 D50% [Gy]

0.75

0.20–4.38

0.76

0.21–2.68

1.33

0.001

0.275

 Dmax [Gy]

1.91

0.54–23.89

2.06

0.46–39.43

7.85

0.019

0.192

 Dmin [Gy]

0.37

0–1.38

0.40

0–1.50

8.11

 < 0.0001

0.375

 V30 Gy [%]

0.00

0.00–0.00

0.00

0.00–0.00

0

1.000

0

 V40 Gy [%]

0.00

0.00–0.00

0.00

0.00–0.00

0

1.000

0

Internal mammary

 Volume [ccm]

7.64

3.80–9.52

7.54

3.70–9.45

-1.31

 < 0.0001

0.522

 Dmean [Gy]

11.17

1.34–44.24

12.77

1.45–39.09

14.32

0.005

0.231

 D50% [Gy]

9.90

1.25–49.93

11.97

1.47–47.57

20.91

0.001

0.273

 Dmax [Gy]

35.21

1.74–64.58

36.02

1.99–59.48

2.3

0.144

0.12

 Dmin [Gy]

1.84

0.55–3.65

1.87

0.60–3.89

1.63

0.127

0.126

 V30 Gy [%]

11.03

0.00–86.55

14.28

0.00–78.74

29.47

0.019

0.193

 V40 Gy [%]

4.83

0.00–82.66

6.45

0.00–67.61

33.54

0.020

0.192

Breast right

 Volume [ccm]

795.47

128.00–2762.68

801.19

121.80–2759.06

0.72

0.023

0.187

 Dmean [Gy]

0.62

0.12–1.81

0.63

0.12–1.69

1.61

0.234

0.098

 D50% [Gy]

0.53

0.00–1.020

0.54

0.00–1.70

1.89

0.661

0.036

 Dmax [Gy]

5.34

0.38–45.77

5.12

0.55–40.31

-4.12

0.046

0.164

 Dmin [Gy]

0.00

0.00–0.22

0.01

0.00–0.59

0

0.019

0.193

 V30 Gy [%]

0.01

0.00–0.86

0.00

0.00–0.00

-1

0.317

0.082

 V40 Gy [%]

0.00

0.00–0.28

0.00

0.00–0.00

0

0.317

0.082

  1. Comparison of mean values (ranges) of DVH parameters for levels I-III, supraclavicular and internal mammary region and contralateral breast and relative changes in percent between DIBH and FB technique using two-sided Wilcoxon signed-rank test and effect size
  2. Abbreviation: DIBH Deep inspiration breath hold, DVH Dose-volume histogram, FB Free breathing