Fig. 4
From: CKAP2L, a crucial target of miR-326, promotes prostate cancer progression
miR-326 plays a carcinostatic role and involves in cell cycle by regulating mitosis. (A) mimic miR-326 transfection impaired the cell proliferation in PC-3 and LNCaP-AI cells. (B-D) miR-326 overexpression decreased the ability of cell proliferation, monolayer colony formation, migration and invasion in PC-3 and LNCaP-AI cells. (E, F) Flow cytometry was carried out to investigate the CKAP2L knockdown or miR-326 overexpression in PC-3 and LNCaP-AI cells. (G) Protein levels of several gene involved in chromosome segregation, spindle assembly and cell cycle after CKAP2L knockdown, miR-326 overexpression, or transfected together. *p < 0.05