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Fig. 1 | BMC Cancer

Fig. 1

From: CKAP2L, a crucial target of miR-326, promotes prostate cancer progression

Fig. 1

mRNA expression of CKAP2L in TCGA and MSKCC prostate cancer cohort with GS. (A, C) CKAP2L is overexpressed in prostate cancer and correlated with high Gleason Score. (B, D) Higher CKAP2L mRNA expression was significantly associated with poorer prognosis in MSKCC and TCGA cohort as Kaplan–Meier curves showing. (E, F) The immunohistochemistry of CKAP2L in BPH, low Gleason Score (GS < 7) and high Gleason Score (GS > 7) prostate cancer samples. (G) CKAP2L protein expression in prostate tumor (T) and adjacent normal tissue(N) samples from 12 high Gleason Score (GS > 7) prostate cancer patients. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns: p > 0.05 

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