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Fig. 2 | BMC Cancer

Fig. 2

From: Contribution and clinical relevance of germline variation to the cancer transcriptome

Fig. 2

Contributions of eQTLs to the cancer transcriptome. (A) Numbers of total variant-expression associations identified across all cancer, where variants refer to inherited SNPs, somatic point mutations and somatic copy number changes. The proportions of these different classes of variants are also indicated. SNP  germline variants, SOMATIC  somatic variants, BOTH  germline and somatic variants. (B) Fraction of variance of individual genes attributable to different genetic factors. Gene experience variance was deconvoluted into all technical and biological factors included in the eQTL model (Methods) and the results for the genetic factors are shown here. Colors correspond to those in (A)

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