Identification and clinical validation of NUSAP1 as a novel prognostic biomarker in ovarian cancer

BMC Cancer

Table 3 Cox regression model analysis of overall survival in patients with epithelial ovarian cancer

Variables	Univariate analysis			Multivariate analysis
Variables	HR	95% CI of HR	P-value	HR	95% CI of HR	P-value
NUSAP1 expression (low vs. high)	6.802	2.039–22.693	0.002*	4.463	1.268–15.704	0.020*
Age (years) (< 60 vs. ≥ 60)	1.886	0.914–3.891	0.086	2.067	0.965–4.427	0.062
FIGO stage (I-II vs. III-IV)	3.043	1.404–6.596	0.005*	2.572	1.005–6.579	0.049*
Tumor grade (1–2 vs. 3)	1.405	0.684–2.886	0.354	0.925	0.414–2.065	0.849
Lymph node metastasis (no vs. yes)	1.702	0.754–3.846	0.201	1.159	0.488–2.753	0.737
Residual tumor size (≤ 1 cm vs. > 1 cm)	7.739	2.503–23.929	0.000*	4.697	1.453–15.188	0.010*
Pathological subtype (nonserous vs. serous)	1.208	0.574–2.546	0.619	2.087	0.848–5.140	0.110

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