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Table 3 Combined analysis

From: Prognostic importance of systemic inflammation and insulin resistance in patients with cancer: a prospective multicenter study

Variables

OS (model 0)

OS (model 4)

 

Crude HR (95%CI)

Crude P

Adjusted HR (95%CI)

Adjusted P

CRP&LHR

 Low CRP & low LHR

1

 

1

 

 Low CRP & high LHR or High CRP & low LHR

1.96 (1.79-2.14)

<0.001

1.37 (1.25-1.50)

<0.001

 High CRP & high LHR

3.19 (2.74-3.71)

<0.001

1.75 (1.49-2.05)

<0.001

P for trend

 

<0.001

 

<0.001

  1. Notes: CRP C-reactive protein, LHR LDL-c/HDL-c ratio, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, HR hazards ratio, CI confidence interval, BMI body mass index, KPS karnofsky performance status
  2. Model 0: Unadjusted
  3. Model 4: Adjusted for age, sex, tumor stage, BMI, tumor types, KPS, surgery, chemotherapy, radiotherapy, smoking, alcohol, nutritional intervention, diabetes, hypertension, and coronary heart disease