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Table 2 WPAI of MPM patients, stratified by current treatment and current line of therapy at data abstraction, for five EU countries (combined data)

From: Malignant pleural mesothelioma: treatment patterns and humanistic burden of disease in Europe

Ā 

Current treatment

Current line of therapy

Doublet

Triplet

Singlet chemotherapy as 1ā€‰L-M

Singlet chemotherapy as SACT

Other treatments

BSC

1-L

1-Lā€‰M

2ā€‰Lā€‰+ā€‰SACT

BSC

Total number of patients with completed PSC who are currently employed

107

62

3

14

13

12

3

70

17

17

3

WPAI Absenteeism

ā€ƒn

75

40

2

11

10

9

3

45

14

13

3

ā€ƒā€ƒMean (SD), %

36.7 (38.5)

24.9 (33.3)

39.9 (22.1)

57.4 (41.3)

35.2 (40.0)

61.6 (41.8)

45.9 (47.0)

25.0 (32.1)

49.9 (42.0)

60.8 (41.5)

45.9 (47.0)

ā€ƒā€ƒMissing

32

22

1

3

3

3

0

25

3

4

0

WPAI Presenteeism

ā€ƒn

83

54

3

8

10

6

2

61

11

9

2

ā€ƒā€ƒMean (SD), %

47.6 (25.5)

47.0 (27.2)

50.0 (17.3)

50.0 (20.0)

44.0 (29.5)

50.0 (17.9)

60.0 (28.3)

47.2 (26.5)

48.2 (20.4)

46.7 (27.4)

60.0 (28.3)

ā€ƒā€ƒMissing

24

8

0

6

3

6

1

9

6

8

1

WPAI Overall Impairment

ā€ƒn

58

35

2

6

8

5

2

40

9

7

2

ā€ƒā€ƒMean (SD), %

47.4 (24.1)

43.2 (22.6)

64.6 (24.9)

54.1 (14.2)

43.3 (31.8)

60.1 (28.8)

68.5 (20.3)

44.6 (23.4)

52.8 (21.3)

50.7 (32.0)

68.5 (20.3)

ā€ƒā€ƒMissing

49

27

1

8

5

7

1

30

8

10

1

Total number with completed PSC

767

399

29

89

97

59

94

475

102

96

94

WPAI Activity Impairment

ā€ƒn

737

384

27

84

93

55

94

457

93

93

94

ā€ƒā€ƒMean (SD), %

56.0 (23.2)

54.1 (21.4)

49.3 (25.6)

50.8 (21.2)

60.2 (28.0)

64.5 (23.9)

61.2 (23.8)

55.2 (22.8)

51.2 (21.3)

59.6 (25.8)

61.2 (23.8)

ā€ƒā€ƒMissing

30

15

2

5

4

4

0

0

9

3

0

  1. Note: EU countries include France, Germany, Italy, Spain, and the UK
  2. BSC Best supportive care; doublet chemotherapy; MPM Malignant pleural mesothelioma; others, other therapies; SACT Systemic anti-cancer therapy; SD Standard deviation; triplet, triplet chemotherapy; WPAI Work Productivity and Activity Impairment questionnaire; 1ā€‰L First-line therapy; 1ā€‰L-M First-line maintenance therapy; 2ā€‰LĀ +Ā SACT SACT at second or later lines