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Table 2 Univariate and multivariate analyses for clinical factors and Rad-score

From: Tumor and peritumor radiomics analysis based on contrast-enhanced CT for predicting early and late recurrence of hepatocellular carcinoma after liver resection

Risk factor

Univariate

Multivariate

 

HR

95% CI

p

HR

95% CI

p

Sex (M/F)

0.962

0.726 ~ 1.488

0.832

   

Age (y)

0.998

0.985 ~ 1.013

0.874

   

Hepatitis B (No /Yes)

1.25

0.851 ~ 1.836

0.256

   

BCLC (0-A/B)

1.152

0.868 ~ 1.731

0.495

   

Child’s class (A/B)

1.112

0.8 ~ 1.545

0.528

   

Largest tumor diameter (cm)

1.125

1.076 ~ 1.175

< 0.01*

1.001

0.952 ~ 1.052

0.96

Tumor number (Single/ Multiple)

1.012

0.686 ~ 1.494

0.953

   

MVI (Negative / Positive)

3.269

2.142 ~ 4.989

< 0.01*

3.092

2.043 ~ 4.68

< 0.01*

AFP level (ng/mL) (≤ 400/>400)

1.239

0.931 ~ 1.648

0.141

   

PT (S)

0.967

0.853 ~ 1.095

0.595

   

TBIL (µmol/L)

0.982

0.961 ~ 1.005

0.122

   

Albumin (g/L)

0.985

0.949 ~ 1.022

0.418

   

ALT(U/L)

0.999

0.994 ~ 1.006

0.943

   

Rad-score

4.584

3.589 ~ 5.855

< 0.01*

4.669

3.554 ~ 6.136

< 0.01*

  1. BCLC The Barcelona Clinic Liver Cancer staging system, MVI Microvascular invasion, AFP Alpha-fetoprotein, ALB: Albumin, ALT Alanine aminotransferase, PT Prothrombin time, TBIL Total bilirubin
  2. *p < 0.05