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Fig. 2 | BMC Cancer

Fig. 2

From: Leukocyte subtyping predicts for treatment failure and poor survival in anal squamous cell carcinoma

Fig. 2

Patients with a peripheral WBC count of ≤ 8 or an ANC ≤ 5 have poor therapy response rates and reduced survival. Peripheral blood specimens were collected from 42 chemo-naïve patients with anal SCC, and subjected to routine complete blood count (CBC) with differential. Patients were separated into two groups: those with a total peripheral white blood cell (WBC) count of < 8, and those with a WBC count of ≥ 8. These groups were compared for (A) primary therapy outcome, (B) overall survival (OS), and (C) disease-specific survival. Also using results of the CBC with differential, patients were evaluated for absolute neutrophil count (ANC), and arranged as having an ANC of < 5 or an ANC of ≥ 5. These groups were similarly evaluated for (D) primary therapy outcome, (E) overall survival (OS), and (F) disease-specific survival. (G,H) Kaplan–Meier curve indicating months of overall survival for patients arranged by primary therapy response or WBC count of above or below 8. (I,J) Kaplan–Meier curve indicating months of disease-specific survival for patients arranged by primary therapy response or a WBC count of above or below 8

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