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Fig. 7 | BMC Cancer

Fig. 7

From: Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer

Fig. 7

Pan-cancer expression profiles of the six key CAF markers in the TCGA dataset. Pan-cancer differential expression profiles of COL1A1, COL1A2, COL3A1, COL5A1, FN1, and SPARC in the TCGA dataset (* p < 0.05, ** p < 0.01, *** p < 0.001). Analysis was performed on TIMER 2.0. Stomach adenocarcinoma (STAD) is highlighted red and five other cancers (COAD: colon adenocarcinoma, GBM: glioblastoma, HNSC: head and neck squamous carcinoma, KIRC: kidney renal cell carcinoma, and THCA: thyroid carcinoma) at which all the six CAF markers were upregulated are highlighted blue in the legends. For a full list of TCGA cancer type abbreviations please refer to https://gdc.cancer.gov/resources-tcga-users/tcga-code-tables/tcga-study-abbreviations

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BMC Cancer

ISSN: 1471-2407

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