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Fig. 5 | BMC Cancer

Fig. 5

From: Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer

Fig. 5

Differential expression and prognostic significance of the six key CAF markers in gastric cancer. A Differential expression of the CAF markers in normal tissues vs. primary stomach adenocarcinoma tissues. B Differential expression of the CAF markers by tumor stage in primary stomach adenocarcinoma (N: normal tissue, S1: stage1, S2: stage2, S3: stage3, S4: stage4). C Differential expression of CAF markers by tumor grade in stomach adenocarcinoma (N: normal tissue, G1:grade1, G2: grade2, G3: grade3). D Kaplan-Meier survival analysis of CAF markers in stomach adenocarcinoma. TCGA data which include 34 normal gastric tissues, and 415 primary stomach adenocarcinoma tissues were used for analysis (* p < 0.05, ** p < 0.01, *** p < 0.001). A-C Analysis was performed on the UALCAN. The numbers of samples in each group in the TCGA dataset are given in parenthesis at the bottom of the figure. D Analysis was performed on TIMER 2.0

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