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Table 2 Univariate analyses of clinicopathological factors between patients with death within 1-year and the others in advanced oropharyngeal cancer patients

From: A predictive model for advanced oropharyngeal cancer patients treated with chemoradiation

Variables

 

Early death patients (n = 43)

Other patients

(n = 104)

P value

Age (years)

≥ 60

20(47%)

62(40%)

0.146

< 60

23(53%)

42(60%)

 

Gender

Male

42(98%)

97(93%)

0.284

Female

1(2%)

7(7%)

 

T

T1 + 2

7(16%)

43(41%)

0.004*

T3 + 4

36(84%)

61(59%)

 

N

N0 + 1 + 2a

14(33%)

51(49%)

0.067

N2b + 2c + 3

29(67%)

53(51%)

 

Stage

III

4(9%)

15(14%)

0.400

IV

39(91%)

89(86%)

 

Disease subsite

Tonsil

25(58%)

69(66%)

0.097

Soft palate

2(5%)

10(10%)

 

Tongue base

3(7%)

11(11%)

 

Pharyngeal wall

13(30%)

14(13%)

 

Previous treated cancer

No

40(93%)

94(90%)

0.608

Yes

3(7%)

10(10%)

 

Syn- or Meta-chronous cancer

No

36(84%)

90(87%)

0.657

Yes

7(16%)

14(13%)

 

Differentiation

Well

0(0%)

3(5%)

0.370

Moderately

8(18%)

29(27%)

 

Poorly

11(26%)

26(25%)

 

Missing

24(56%)

46(43%)

 

HPV (P16)

Positive

7(16%)

32(31%)

0.086

Negative

7(16%)

22(21%)

 

Missing

29(68%)

50(48%)

 

Smoking habit

No

10(23%)

23(22%)

0.943

Yes, quitted

12(28%)

27(26%)

 

Yes, persistent

21(49%)

54(52%)

 

Body Height (cm)

≥163

38(88%)

72(69%)

0.015*

< 163

5(12%)

32(31%)

 

Body Weight (kg)

≥60

22(51%)

73(70%)

0.014*

< 60

21(49%)

31(30%)

 

BMI (kg/m2)

≥22

18(42%)

69(66%)

0.006*

< 22

25(58%)

35(34%)

 

Hemoglobulin (gm/dl)

≥ 13.5

8(19%)

61(59%)

0.000*

< 13.5

35(81%)

43(41%)

 

Lymphocyte count (103/μl)

≥1.85

16(37%)

27(26%)

0.173

< 1.85

27(63%)

77(74%)

 

Monocyte count (102/μl)

≥0.56

21(49%)

43(41%)

0.405

< 0.56

22(51%)

61(59%)

 

Platelet count (103/μl)

≥239

34(79%)

44(42%)

0.000*

< 239

9(21%)

60(58%)

 

Neutrophil count (103/μl)

≥7.5

17(40%)

28(17%)

0.004*

< 7.5

26(60%)

86(83%)

 

LMR

≥1.9

30(70%)

80(77%)

0.363

< 1.9

13(30%)

24(23%)

 

PLR

≥157

28(65%)

49(47%)

0.047*

< 157

15(35%)

55(53%)

 

NLR

≥5.1

19(44%)

28(27%)

0.041*

< 5.1

24(56%)

76(63%)

 

SIRI

≥553.7

10(23%)

7(7%)

0.004*

< 553.7

33(77%)

97(93%)

 

SII

≥1820

16(37%)

7(7%)

0.000*

< 1820

27(63%)

97(93%)

 
  1. *: p < 0.05
  2. LMR lymphocyte to monocyte ratio; PLR platelet to lymphocyte ratio; NLR neutrophil to lymphocyte ratio; SII systemic immune inflammation; SIRI systemic inflammation response index