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Table 1 Characteristics and clinicopathological parameters of the recruited advanced oropharyngeal cancer patients

From: A predictive model for advanced oropharyngeal cancer patients treated with chemoradiation

 

N (%) or mean ± SD (range) or median (range, IQR)

Age (years)

61.7 ± 9.9(36–93)

Gender (Male/Female)

139(95%)/8(5%)

T classification (T1 + 2/ T3 + 4)

50(33%)/97(67%)

N classification (N0/N1/N2/N3)

12(8%)/26(18%)/92(63%)/17(11%)

Stage (III/ IVa/ IVb)

19(13%)/96(65%)/32(22%)

Body Height (cm)

166.7 ± 6.1(152–185)

Body Weight (kg)

64.4 ± 12.4(36–100)

BMI (kg/m2)

23.2 ± 4.1(12.5–35.4)

Tumor side (Right/Left)

62(42%)/85(58%)

Disease subsite (Tonsil/ Soft palate/ Tongue base/ Pharyngeal wall)

94(64%)/12(8%)/14(10%)/27(18%)

Previous treated cancer

13(9%)

  Oral cancer

7

  Esophageal cancer

3

  Hypopharyngeal cancer

1

  Hepatocellular carcinoma

1

  Rectal cancer

1

Syn- or Meta-chronous cancer

21(14%)

  Esophageal cancer

10

  Oral cancer

4

  Lung cancer

2

  Hepatocellular carcinoma

1

  Oral and hypopharyngeal cancer

1

  Hypopharyngeal cancer

1

  Breast cancer

1

  Thyroid cancer

1

Differentiation (Well/Moderately/Poorly/Missing)

3(2%)/37(25%)/37(25%)/70(48%)

HPV (p16) (Positive/Negative/Missing)

29(20%)/39(26%)/79(54%)

Smoking habit (No/Yes)

33(22%)/114(78%)

Hemoglobulin (gm/dl)

13.0 ± 2.2(4.1–16.5)

Lymphocyte count (103/μl)

1.6 ± 0.8(0.5–6.4)

Monocyte count (102/μl)

0.6 ± 0.4(0.2–4.1)

Platelet count (103/μl)

254.2 ± 85.4(91.0–475.0)

Neutrophil count (103/μl)

6.0 ± 2.8(1.2–17.2)

LMR

3.2 ± 1.8(0.5–8.9)

PLR

184.3 ± 102.0(36.7–697.2)

NLR

4.5 ± 2.9(0.9–16.2)

SIRI

264.3 ± 225.3(21.8–1391.4)

SII

1158.2 ± 935.5(133.0–5209.9)

Median follow-up (range, IQR) (days)

599(315–1446, 1131)

Death within 1 year

43(29%)

Disease Persistence

51(35%)

Recurrence

40(27%)

 Local

16

 Regional

7

 Locoregional

1

 Distant

20

  1. LMR Lymphocyte to monocyte ratio, PLR Platelet to lymphocyte ratio, NLR Neutrophil to lymphocyte ratio, SII Systemic immune inflammation, SIRI Systemic inflammation response index, IQR Interquartile range