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Fig. 5 | BMC Cancer

Fig. 5

From: Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS)

Fig. 5

ASPP2κ-interference inhibits cell migration in rhabdomyosarcoma cells. A, C Quantitative analysis of wound-healing rates in rhabdomyosarcoma cells. Statistical test: two-way ANOVA. B, D. Linear regression graph of the wound-healing speed. EV, empty vector. **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05. E Illustration of representative wound healing experiments for the shASPP2κ-RD and ssRMS cell lines for five time points (t = 0-8 h). Graphical display of wound healing computed by ImageJ. Blue curve, overlay of wound margin at the start of experiment; red curve, wound closure at a given time point; experiments were performed in technical triplicates

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BMC Cancer

ISSN: 1471-2407

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