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Fig. 2 | BMC Cancer

Fig. 2

From: MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment

Fig. 2

MIF and CXCR4 are expressed in high-risk NB tumors and cell lines. Violin plots showing CXCR4, CD74, MIF and CXCL12 gene expression across A) different NB stages and B) risk groups, low/intermediate-risk (LIR) and High-risk (HR) (GSE62564). *P < 0.01 (One-way ANOVA, Kruskal Wallis test). C) NB patient overall survival associated with CXCR4, CXCL12, CD74 and MIF expression levels (GSE62564, Kaplan-Meier analysis). High expression is shown in green and low expression in red. Total number of patients and (positive events) per group are also shown. Percentage of D) CXCR4 and E) CD74 positive cells in a NB cell line panel analyzed by flow cytometry (n = 3)

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BMC Cancer

ISSN: 1471-2407

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