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Table 1 Clinical characteristics of patients in the unweighted and weighed population

From: Necessity of external iliac lymph nodes and inguinal nodes radiation in rectal cancer with anal canal involvement

Characteristic level Overall Unweighted population Weighted population (IPTW)
Rb group, n (%) P group, n (%) p Rb group, % P group, % p
n   399 290 109     
Gender (%)
  Female 170 (42.6) 116 (40.0) 54 (49.5) 0.109 42.5 47.1 0.441
  Male 229 (57.4) 174 (60.0) 55 (50.5)   57.5 52.9  
Age
   < 60 165(41.4) 194 (66.9) 71 (65.1) 0.832 68.3 62.8 0.328
   ≥ 60 134(33.6) 96 (33.1) 38 (34.9)   31.7 38.2  
Concurrent chemotherapy regimen (%)
  Single 232 (58.1) 177 (61.0) 55 (50.5) 0.001 59.5 57.4 0.840
  Combined 143 (35.8) 103 (35.5) 40 (36.7)   35.0 35.6  
  None 24 (6.0) 10 (3.4) 14 (12.8)   5.4 7.0  
Postoperative chemotherapy (%)
  no 107 (26.9) 70 (24.2) 37 (33.9) 0.068 27.8 32.3 0.414
  Yes 291 (73.1) 219 (75.8) 72 (66.1)   72.2 67.7  
Radiotherapy strategies (%)
  LCRT 36 (9.0) 26 (9.0) 10 (9.2)  < 0.001 8.7 7.9 0.849
  LCRT + SIB 344 (86.2) 258 (89.0) 86 (78.9)   86.5 85.8  
  SCRT 19 (4.8) 6 (2.1) 13 (11.9)   4.8 6.3  
Number of dissected lymph nodes (%)
   < 12 195 (48.9) 151 (52.1) 44 (40.4) 0.006 49.6 46.0 0.245
   ≥ 12 195 (48.9) 136 (46.9) 59 (54.1)   49.1 49.5  
  none 9 (2.3) 3 (1.0) 6 (5.5)   1.3 4.5  
cT (%)
  cT1-3 158 (41.6) 122 (44.2) 36 (34.6) 0.115 44.3 34.6 0.107
  cT4 222 (58.4) 154 (55.8) 68 (65.4)   55.7 65.4  
cN (%)
  cN- 43 (11.3) 30 (10.9) 13 (12.5) 0.790 10.4 11.1 0.844
  cN +  337 (88.7) 246 (89.1) 91 (87.5)   89.6 88.9  
CEA, ng/nl (median [IQR]) 3.3
[1.9,7.3]
3.5
[2.0, 7.6]
3.0
[1.7,6.1]
0.252 3.4
[1.9,7.6]
2.8
[1.7, 5.8]
0.191
CA199, U/ml (median [IQR]) 12.6
[6.9,22.0]
12.5
[6.6,21.3]
12.8
[7.9,28.2]
0.112 12.7
[6.6, 21.7]
11.9
[7.9,25.8]
0.394
  1. LCRT Long course radiotherapy, SIB simultaneous integrated boost, SCRT short course radiotherapy, CEA carcinoembryonic antigen, CA199 carbohydrate antigen 19–9