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Table 2 Univariate survival analysis for the prognostic value of hub genes in the TCGA final discovery cohort

From: Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients

Gene

HR

HR.95%Low

HR.95%High

P value

ALOXE3

0.9723

0.9386

1.0073

0.1195

ANXA9

0.9758

0.9420

1.0107

0.1714

FUT2

0.9803

0.9541

1.0072

0.1492

MUC15

1.0238

0.9913

1.0574

0.1535

ASPG

0.9579

0.9044

1.0146

0.1428

PI3

1.0000

0.9999

1.0000

0.1149

CSTA

0.9997

0.9994

1.0001

0.1825

BNIPL

0.9868

0.9682

1.0057

0.1709

HPSE

0.9639

0.9138

1.0167

0.1768

SPRR1A

0.9999

0.9999

1.0000

0.1046

GCNT3

1.0336

1.0042

1.0638

0.0248

LY6G6C

0.9962

0.9909

1.0016

0.1647

PRSS3

0.9933

0.9834

1.0034

0.1913

ECM1

0.9983

0.9959

1.0007

0.1583

ALOX12B

0.9886

0.9777

0.9996

0.0420

PTGR1

1.0040

1.0002

1.0077

0.0383

TXNRD1

1.0033

0.9994

1.0073

0.0997

NQO1

1.0018

0.9995

1.0042

0.1270

ASNS

1.0169

1.0017

1.0324

0.0294

SLC7A11

1.0092

0.9981

1.0205

0.1047

G6PD

1.0019

0.9995

1.0044

0.1215

ENO2

1.0095

0.9973

1.0219

0.1284

SRXN1

1.0311

0.9864

1.0778

0.1753

GNGT1

1.1803

1.0139

1.3740

0.0325

ADH7

1.0047

1.0009

1.0086

0.0162

CLDN8

1.0242

0.9933

1.0560

0.1260

ODC1

0.9994

0.9985

1.0003

0.1863

CYP2S1

1.0039

0.9993

1.0086

0.0984