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Fig. 4 | BMC Cancer

Fig. 4

From: Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients

Fig. 4

Identification of DDR- and TM- related hub genes in the TCGA final discovery cohort. A Heatmap of clustered top 100 differentially expressed genes (DEGs) between DDR_high/TM_high and DDR_high/TM_low groups. B-D WGCNA algorithm screened out seven eigengenes module (blue, green, red, pink, black, brown, and grey) based on DDR and TM status. E-F The top 50 hub genes selected in black and brown modules by protein-to-protein network method; respectively

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