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Table 1 Relationships between the preoperative and postoperative LCR and clinicopathological variables in patients with gastric cancer

From: Combined analysis of preoperative and postoperative lymphocyte-C-reactive protein ratio precisely predicts outcomes of patients with gastric cancer

 

Pre-LCR

p value

Post-LCR

p value

Age

 

< 0.0001

 

< 0.001

  < 75 (n = 298)

45,508 ± 52,948

 

49,304 ± 55,861

 

  ≥ 75 (n = 157)

28,532 ± 36,722

 

26,652 ± 35,818

 

Gender

 

0.001

 

0.0007

  Male (n = 332)

34,784 ± 44,367

 

36,508 ± 45,063

 

  Female (n = 123)

52,786 ± 56,686

 

54,928 ± 62,532

 

Tumor size

 

0.002

 

0.294

  < 4 cm (n = 277)

44,611 ± 53,185

 

43,890 ± 53,136

 

  ≥ 4 cm (n = 178)

31,930 ± 39,383

 

37,749 ± 47,319

 

Differentiation

 

0.421

 

0.289

  Differentiated (n = 261)

37,479 ± 47,514

 

38,031 ± 46,889

 

  Poorly differentiated (n = 194)

42,571 ± 50,015

 

46,137 ± 55,790

 

Depth of invasion

 

0.006

 

0.55

  T1 (n = 287)

43,386 ± 48,998

 

43,027 ± 52,705

 

  T2/3/4 (n = 168)

33,268 ± 47,398

 

38,858 ± 47,912

 

Lymph node metastasis

 

0.013

 

0.582

  Absent (n = 325)

42,652 ± 49,065

 

42,533 ± 51,809

 

  Present (n = 130)

32,147 ± 46,790

 

38,874 ± 48,923

 

Lymphatic involvement

 

0.006

 

0.183

  Absent (n = 199)

46,685 ± 53,217

 

44,284 ± 51,689

 

  Present (n = 256)

34,182 ± 44,032

 

39,314 ± 50,405

 

Vascular involvement

 

0.025

 

0.203

  Absent (n = 229)

45,495 ± 53,053

 

42,729 ± 49,083

 

  Present (n = 226)

33,728 ± 42,956

 

40,230 ± 52,901

 

Stage

 

0.063

 

0.681

  I (n = 307)

41,935 ± 48,565

 

42,928 ± 52,670

 

  II/III (n = 148)

34,912 ± 48,517

 

38,500 ± 47,296

 

CEA

 

0.184

 

0.045

  < 5 ng/mL (n = 396)

41,296 ± 50,745

 

43,062 ± 51,413

 

  ≥ 5 ng/mL (n = 59)

28,604 ± 28,539

 

30,920 ± 46,980

 

CA19-9

 

0.285

 

0.571

  < 37 ng/mL (n = 417)

40,670 ± 50,059

 

42,401 ± 52,312

 

  ≥ 37 ng/mL (n = 38)

28,463 ± 25,994

 

31,464 ± 31,666

 

Gastrectomy

 

0.516

 

0.796

  Distal/proximal (n = 350)

40,438 ± 49,015

 

41,099 ± 49,566

 

  Total (n = 105)

37,026 ± 47,358

 

42,783 ± 55,645

 

Lymphadenectomy

 

0.003

 

0.335

  D0/D1/D1 + (n = 315)

43,373 ± 49,489

 

42,477 ± 50,033

 

  D2 (n = 140)

31,274 ± 45,632

 

39,262 ± 53,148

 

Operation time

 

0.092

 

0.878

  < Median (n = 227)

36,386 ± 44,043

 

42,071 ± 50,172

 

  ≥ Median (n = 228)

42,900 ± 52,658

 

40,907 ± 51,865

 

Postoperative complications

 

0.012

 

< 0.0001

  Absent (n = 314)

43,607 ± 52,275

 

46,013 ± 51,861

 

  Present (n = 141)

30,839 ± 37,936

 

31,411 ± 47,591

 
  1. All results are expressed as the mean ± standard deviation
  2. CEA Carcinoembryonic antigen, CA19-9 Carbohydrate antigen 19–9
  3. The median operation time was 324 min
  4. Postoperative complications were considered grade 2 or higher according to the Clavien–Dindo classification
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BMC Cancer

ISSN: 1471-2407

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