Table 4 Univariable Cox regression overall survival
Variable | Hazard ratio (95% CI) | P value |
|---|---|---|
Pre-treatment BM DTC status | 2.0 (1.1–3.7) | 0.034 |
Pre-treatment BM KRT7/8 DTC status | 7.7 (3.0–20) | 0.000024 |
Age (> 67 years) | 0.92 (0.50–1.7) | 0.78 |
Sex (Female vs male) | 0.82 (0.44–1.5) | 0.54 |
Clinical T stage (T4 vs T1/2/3) | 0.49 (0.26–0.92) | 0.028 |
Primary tumor localization (head/body vs tail) | 0.46 (0.20–1.1) | 0.07 |
Clinical N stage (N1 vs N0) | 0.82 (0.45–1.5) | 0.52 |
Clinical M stage (M1 vs M0) | 1.52 (0.75–3.1) | 0.25 |
Metastatic sites (multiple organs vs single) | 0.98 (0.46–2.1) | 0.95 |
ECOG status (2 vs 1/0) | 6.4 (2.3–18) | 0.00031 |
First-line treatment (FOLFIRINOX vs other) | 0.47 (0.26–0.87) | 0.0017 |