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Table 1 Univariate and multivariate analysis of the prognostic value of GSTM5 expression regarding OS in patients with LUAD

From: Aberrant expression of GSTM5 in lung adenocarcinoma is associated with DNA hypermethylation and poor prognosis

Parameters Univariate analysis Multivariate analysis
P HR 95%Cl (lower/upper) P HR 95%Cl (lower/upper)
Age 0.307 1.008 0.993 1.024     
Gender
  Female vs. Male 0.842 0.971 0.724 1.302     
Pathological stage
  I/II vs. III/IV < 0.001 0.384 0.281 0.526     
Targeted molecular therapy
  Yes vs. No 0.410 0.869 0.621 1.214     
Smoking History
  Yes vs. No 0.617 0.900 0.596 1.360     
Radiation therapy
  Yes vs. No < 0.001 0.500 0.340 0.735     
GSTM5 expression 0.003 0.848 0.762 0.945 0.023 0.884 0.794 0.981
Longest tumor dimension 0.929 0.983 0.681 1.421     
  1. Note: Multivariate analysis was performed by setting pathological stages, radiation therapy and GSTM5 expression as covariates
  2. Bold indicates P< 0.05