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Table 1 Univariate and multivariate analysis of the prognostic value of GSTM5 expression regarding OS in patients with LUAD

From: Aberrant expression of GSTM5 in lung adenocarcinoma is associated with DNA hypermethylation and poor prognosis

Parameters

Univariate analysis

Multivariate analysis

P

HR

95%Cl (lower/upper)

P

HR

95%Cl (lower/upper)

Age

0.307

1.008

0.993

1.024

    

Gender

  Female vs. Male

0.842

0.971

0.724

1.302

    

Pathological stage

  I/II vs. III/IV

< 0.001

0.384

0.281

0.526

    

Targeted molecular therapy

  Yes vs. No

0.410

0.869

0.621

1.214

    

Smoking History

  Yes vs. No

0.617

0.900

0.596

1.360

    

Radiation therapy

  Yes vs. No

< 0.001

0.500

0.340

0.735

    

GSTM5 expression

0.003

0.848

0.762

0.945

0.023

0.884

0.794

0.981

Longest tumor dimension

0.929

0.983

0.681

1.421

    
  1. Note: Multivariate analysis was performed by setting pathological stages, radiation therapy and GSTM5 expression as covariates
  2. Bold indicates P< 0.05
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BMC Cancer

ISSN: 1471-2407

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