Fig. 8

The GSEA analysis showed the potential downstream signaling of GSTM5. A Heatmap of the top 50 features for each phenotype in single GSTM5 gene enrichment analysis in TCGA LUAD database. B Low GSTM5 expression group was enriched in spliceosome, mismatch repair, base excision repair, RNA degradation gene sets. C Gene sets enriched in phenotype of low GSTM5 expression group. ES, enrichment score; NES, normalized ES; NOM P-val, normalized P-value