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Fig. 1 | BMC Cancer

Fig. 1

From: Simulating the restoration of normal gene expression from different thyroid cancer stages using deep learning

Fig. 1

Expression profiles of 19,239 genes in THCA tumor and normal thyroid samples. (A) The t-SNE plot shows RNA expression profiles of normal thyroid tissue from GTEx, normal thyroid tissue from TCGA, THCA tumor samples from TCGA of various stages, and all the perturbed samples with GTEx normal thyroid tissue as the target. (B) The representative heatmap shows the expression vectors of one Stage 3 THCA tumor sample (X), the perturbations applied (P), the perturbed sample (X + P), and average for the target class of normal thyroid tissue from GTEx (mu_T). Missing values in the training and perturbed sample GEMs were imputed with the minimum value of the training GEM

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BMC Cancer

ISSN: 1471-2407

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