Fig. 2

SPECT/CT-guided targeted bone marrow biopsy in the right ilium. Posterior bone scintigraphy, SPECT/CT fusion tomography image, biopsy image, and biopsy pathology image of a patient with invasive ductal carcinoma of the right breast 3 years after surgery (female, 29-year-old). A. The posterior bone scintigraphy suggested multiple abnormal increases in bone metabolism in the whole body and an abnormal increase in metabolism of the right ilium (black arrow). B, C SPECT/CT fusion tomography results indicated that the bone density in the right ilium that exhibited increased metabolism had significantly increased. D SPECT/CT-guided percutaneous biopsy of the biological target in the right ilium. E Pathological examination results suggested metastatic breast invasive ductal carcinoma, and light microscopy results revealed metastatic adenocarcinoma cells in blood clots (HE × 100)