Fig. 6

PI3K/Akt inhibitors confirmed that EEF1D could regulate PI3K/Akt signal pathway. A and B PI3K/Akt inhibitors would decrease viability of EEF1D knockout/knockdown cells less than control cells; A SKOV3/DDP cell lines, B SKOV3 cell lines. C and D PI3K/Akt inhibitors had the similar effects from knockout/knockdown cells; C SKOV3/DDP cell lines, D SKOV3 cell lines. Data are mean ± SD, the experiment was performed with sextuplicate in three independent sets, ^*P < 0.05, ^**P < 0.01 compared with DDP intervention alone in the same cell line; ^#P < 0.05, ^##P < 0.01 compared with SKOV3 or SKOV3/DDP in the same drug intervention