Fig. 2From: Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatinKnocking down or out EEF1D gene expression increased the sensitivity of human ovarian cancer cells to DDP in vitro. A The viabilities of ovarian cancer cells with DDP treatment in SKOV3 cell line stably knocked down and out EEF1D gene. B The viabilities of ovarian cancer cells with DDP treatment in SKOV3/DDP cell line stably knocked down and out EEF1D gene. C The viabilities of ovarian cancer cells with DDP treatment in Human primary ovarian cancer cells transiently knocked down EEF1D gene in 5 ovarian cancer patients. Data in A, B and C are mean ± SD, the experiment was performed with sextuplicate in three independent sets, *P < 0.05, **P < 0.01 compared with SKOV3, SKOV3/DDP or POCC intervened by DDP at the same concentration, #P < 0.05, ##P < 0.01 compared with SKOV3/KD, SKOV3/DDP/KD or POCC/scrambled shRNA intervened by DDP at the same concentration. D Representative flow cytometry dot plot of human ovarian cancer cell lines stained with annexin-V-FITC and PI. E Histogram of apoptosis rates of human ovarian cancer cell lines. F Representative flow cytometry dot plot of human primary ovarian cancer cells stained with annexin-V-FITC and PI in 5 ovarian cancer patients. G Histogram of apoptosis rates of POCC. The data in E and G are shown as means ± SD (E:n = 6; G:n = 10), **P < 0.01 vs. control, KD or KO group, respectively; ##P < 0.01 vs. control+DDP group. POCC: primary ovarian cancer cellBack to article page