Table 3 Univariate regression and multivariate survival method (Overall Survival) of prognostic covariates in patients with LUAD
Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
Pathologic stage | 518 | Â | Â | Â | Â |
 Stage I& II | 411 | Reference |  |  |  |
 Stage III& IV | 107 | 2.664 (1.960–3.621) | < 0.001 | 2.414 (1.765–3.303) | < 0.001 |
 T stage | 523 |  |  |  |  |
 T1&T2 | 457 | Reference |  |  |  |
 T3&T4 | 66 | 2.317 (1.591–3.375) | < 0.001 | 2.016 (1.321–3.076) | 0.001 |
N stage | 510 | Â | Â | Â | Â |
 N0&N1 | 437 | Reference |  |  |  |
 N2&N3 | 73 | 2.321 (1.631–3.303) | < 0.001 | 1.958 (1.294–2.962) | 0.001 |
M stage | 377 | Â | Â | Â | Â |
 M0 | 352 | Reference |  |  |  |
 M1 | 25 | 2.136 (1.248–3.653) | 0.006 | 1.818 (1.023–3.231) | 0.042 |
 SEMA4B | 526 | 1.325 (1.151–1.526) | < 0.001 | 1.224 (1.030–1.455) | 0.022 |