Table 4 Univariate and multivariate analysis of disease-free survival

Age (> / ≤ 68, years)

2.039 (1.362–3.053)

0.001*

1.876 (1.250–2.814)

0.002*

Sex (female/male)

0.846 (0.572–1.251)

0.402

BMI (> / ≤ 23.4 kg/m²)

0.721 (0.491–1.059)

0.096

Hypertension (yes/no)

1.003 (0.686–1.465)

0.989

Tumor site (colon/ rectum)

1.364 (0.932–1.995)

0.268

TNM stage (IV/III/II/I)

1.551 (1.217–1.975)

 < 0.01*

1.502 (1.173–1.924)

0.001*

Vessel invasion (yes/no)

3.028 (1.521–6.027)

0.002*

2.515 (1.243–5.087)

0.010*

Perineural invasion (yes/no)

2.250 (0.707–7.160)

0.170

Adjuvant therapy (yes/no)

1.622 (0.750–3.507)

0.219

Smoking (yes/no)

1.148 (0.779–1.692)

0.485

Drinking (yes/no)

1.243 (0.833–1.855)

0.287

Family history (yes/no)

1.316 (0.536–3.230)

0.549

CHD (yes/no)

1.195 (0.656–2.179)

0.561

Overall complications (yes/no)

2.123 (1.452–3.104)

 < 0.01*

1.834 (1.217–2.765)

0.004*

Major complications (yes/no)

3.981 (2.070–7.657)

 < 0.01*

2.185 (1.070–4.462)

0.032*