Table 3 Univariate and multivariate analysis of overall survival

Age (> / ≤ 68, years)

1.039 (1.016–1.062)

0.001*

2.089 (1.353–3.227)

0.001*

Sex (female/male)

0.798 (0.528–1.207)

0.286

BMI (> / ≤ 23.4 kg/m²)

0.665 (0.443–0.999)

0.049*

0.704 (0.466–1.062)

0.094

Hypertension (yes/no)

0.980 (0.659–1.459)

0.922

Tumor site (colon/ rectum)

1.396 (0.936–2.048)

0.102

TNM stage (IV/III/II/I)

1.672 (1.294–2.162)

< 0.01*

1.601 (1.229–2.086)

< 0.01*

Vessel invasion (yes/no)

3.517 (1.760–7.026)

< 0.01*

2.759 (1.339–5.683)

0.006*

Perineural invasion (yes/no)

2.627 (0.823–8.379)

0.103

Adjuvant therapy (yes/no)

1.024 (0.375–2.797)

0.963

Smoking (yes/no)

1.202 (0.802–1.803)

0.373

Drinking (yes/no)

1.334 (0.880–2.022)

0.175

Family history (yes/no)

1.406 (0.572–3.459)

0.458

CHD (yes/no)

1.358 (0.742–2.486)

0.321

Overall complications (yes/no)

2.312 (1.554–3.439)

< 0.01*

1.936 (1.258–2.980)

0.003*

Major complications (yes/no)

4.398 (2.278–8.493)

< 0.01*

2.412 (1.157–5.029)

0.019*