Table 1 Characteristics of study populations with stage III colon cancer eligible for adjuvant chemotherapy following surgical resection
Characteristics | Study population for adjuvant chemotherapy initiation ≤ 8 weeks of surgical resection (n = 222) n (%) | Study population for adjuvant chemotherapy initiation ≤ 12 weeks of surgical resection (n = 310) n (%) |
|---|---|---|
Age (years) | ||
 Median (Interquartile range) | 56 (50–61) | 56 (50–61) |
Sex | ||
 Female | 126 (57) | 175 (56) |
 Male | 96 (43) | 135 (44) |
Race/Ethnicity | ||
 Non-Hispanic White | 77 (35) | 112 (36) |
 Non-Hispanic Black | 67 (30) | 87 (28) |
 Hispanic | 57 (26) | 87 (28) |
 Non-Hispanic other | 21 (9.5) | 24 (7.7) |
Insurance coverage | ||
 Uninsured without hospital-based medical assistance program | 50 (23) | 73 (24) |
 Uninsured with hospital-based medical assistance program | 107 (48) | 137 (44) |
 Insureda | 65 (29) | 100 (32) |
Marital status | ||
 Single | 89 (40) | 124 (40) |
 Married | 70 (32) | 99 (32) |
 Divorced/Separated/Widowed | 63 (28) | 87 (28) |
Body Mass Index (BMI) | ||
 BMI < 25 | 56 (25) | 78 (25) |
 25 ≤ BMI < 30 | 59 (27) | 87 (28) |
 BMI ≥ 30 | 107 (48) | 145 (47) |
NCI comorbidity index | ||
 0 | 168 (76) | 235 (76) |
  > 0 | 54 (24) | 75 (24) |
Tumor grade | ||
 Well/Moderately differentiated | 191 (86) | 265 (85) |
 Poorly differentiated/Undifferentiated | 31 (14) | 45 (15) |
Surgery procedure | ||
 Partial colectomy/Segmental resection | 106 (48) | 143 (46) |
 Subtotal/Hemicolectomy/Total colectomy | 116 (52) | 167 (54) |
Timing of adjuvant chemotherapy initiation | ||
 Initiation ≤ 8 weeks of surgical resection | 81 (36) | N/A |
 No initiation ≤ 8 weeks of surgical resection | 141 (64) | N/A |
 Initiation ≤ 12 weeks of surgical resection | N/A | 150 (48) |
 No initiation ≤ 12 weeks of surgical resection | N/A | 160 (52) |