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Fig. 1 | BMC Cancer

Fig. 1

From: An iron metabolism and immune related gene signature for the prediction of clinical outcome and molecular characteristics of triple-negative breast cancer

Fig. 1

Study flow chart. Firstly, 2087 TNBC-DEGs and 56 IMRGs were identified. Next, a Pearson correlation analysis was performed between these two datasets and then we acquired 1244 TNBC-IMRGs. Subsequently, this dataset was integrated with the BRCA prognostic genes to obtain 30 candidate prognostic TNBC-IMRGs. Through LASSO analysis, a five-IMRGs signature was constructed. Survival analysis and ROC curve were performed to identify the prognostic value. Differences of molecular characteristics were evaluated between high- and low- risk groups. Finally, a combined model was constructed by combining the gene signature with the clinical variables

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