Mast cell marker gene signature in head and neck squamous cell carcinoma

BMC Cancer

Table 3 The ten representative KEGG pathways in high- and low-risk groups

Names	Size	ES	NES	NOM P	FDR
High-risk group
KEGG_Protein export	24	0.72	1.94	0.002	0.097
KEGG_Aminoacyl-tRNA biosynthesis	41	0.66	1.88	0.006	0.103
KEGG_RNA polymerase	28	0.64	1.84	0.004	0.092
KEGG_Pentose phosphate pathway	27	0.52	1.61	0.037	0.239
KEGG_Amino sugar and nucleotide sugar metabolism	43	0.46	1.58	0.032	0.224
KEGG_Arginine and proline metabolism	54	0.42	1.53	0.038	0.211
Low-risk group
KEGG_T cell receptor signaling pathway	108	−0.7	−2.3	0	0
KEGG_Cytokine-cytokine receptor interaction	264	−0.63	−2.26	0	0
KEGG_Chemokine signaling pathway	188	−0.63	−2.23	0	0
KEGG_Natural killer cell mediated cytotoxicity	132	−0.63	−2.19	0	0
KEGG_Cell adhesion molecules_CAMs	131	−0.68	−2.19	0	0
KEGG_Jak-STAT signaling pathway	155	−0.6	−2.16	0	0.001
KEGG_B cell receptor signaling pathway	75	−0.65	−2.13	0	0.001
KEGG_Antigen processing and presentation	81	−0.68	−2.05	0	0.001
KEGG_Alpha-Linolenic acid metabolism	19	−0.7	−1.92	0	0.008
KEGG_Arachidonic acid metabolism	58	−0.55	−1.91	0	0.009

ISSN: 1471-2407