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Fig. 3 | BMC Cancer

Fig. 3

From: Mir-675-5p supports hypoxia-induced drug resistance in colorectal cancer cells

Fig. 3

Effects of AntagomiR-675-5p treatment in cell viability in chronic hypoxic conditions. A: Cell viability assay (MTT Assay) in HCT116 and SW480 transfected with AntagomiR-675-5p or Scrambled Negative Control (Scr) and grown in the hypoxic chamber for 72 h. Data are expressed as cell viability percentage compared to cells transfected with Scr. B: Cell viability assay (MTT Assay) in HCT116 and SW480 transfected with AntagomiR-675-5p or Scramble Negative Control (Scr) and treated or not for 72 h of hypoxia with 5-FU (10 μM). Data are expressed as the mean ± SD of three biological replicates. Statistical analyses: Student’s t-test was used for Fig. A, Ordinary one-way ANOVA with Bonferroni’s multiple comparison test were used in Fig. B (* = p < 0.05; ** = p < 0.01; **** = p < 0.0001)

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