Fig. 6

Estimation of Tumor-Infiltrating Cells and Immunotherapy significance. A Patients in the high-risk group were more positively associated with tumor-infiltrating immune cells such as macrophages, monocytes, and CD8+ T cells, whereas they were negatively associated with fibroblasts and CD4+ T cells, as shown by Spearman correlation analysis. Correlation between prognostic risk signature with hub immune checkpoint genes. B Correlation between prognostic risk signature and CD274, C Correlation between prognostic risk signature and CTLA4, D Correlation between prognostic risk signature and HAVCR2. E Correlation between prognostic risk signature and IDO1. F Correlation between prognostic risk signature and PDCD1. G Correlation between prognostic risk signature and PDCD1LG2. Estimation of Risk Score in Chemotherapeutic Effect. H Sensitivity analysis of Cisplatin in patients at high and low risk score. I Sensitivity analysis of Gemcitabine in patients at high and low risk score. J Sensitivity analysis of Metformin in patients at high and low risk score. K Sensitivity analysis of Nilotinib in patients at high and low risk score