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Fig. 5 | BMC Cancer

Fig. 5

From: PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment

Fig. 5

Quantitative PCR (qPCR) experiments confirm that the ectopic expression of hPARG in 3 T3 cells changes the expression profiles of genes implicated in tumorigenesis, specifically chemokines. Differential expression for hPARG+ cells vs control. RNA-seq fold change results are in blue, qPCR fold change is shown in red. Fold change based on 3 biological replicates, error bars for qPCR are in SEM. (insert) Scatterplot of fold change for differentially expressed genes from RNA-seq analyses plotted against qPCR expression fold change results. Pearson’s correlation value of fold change calculated via qPCR and RNA-seq = 0.98 with a P-value < 0.00001

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