A stratification model of hepatocellular carcinoma based on expression profiles of cells in the tumor microenvironment

Table 1 Clinical characteristics of patients of different subtypes in the Cancer Genome Atlas cohort

Variable	C1	C2	C3	p value
Gender				0.561
Female	47	19	51
Male	82	39	116
Age (years)				0.371
< 60	56	31	77
≥ 60	73	26	90
Grade				0.330
I	17	9	25
II	69	25	75
III	39	20	58
IV	1	3	8
AJCC stage				0.896
I	55	29	82
II	31	14	36
III	27	13	42
IV	3	0	2
Vascular invasion				0.752
None	71	32	93
Micro	33	11	45
Macro	6	3	5
TP53				0.447
Mutant	35	21	52
Wild-type	94	37	115
CTNNB1				< 0.001
Mutant	17	14	63
Wild-type	112	44	104
FGF19				< 0.001
Amplification	5	12	7
Wild-type	124	46	160

ISSN: 1471-2407