Table 1 Multivariate survival analysis of risk factors for nasopharyngeal carcinoma patients
From: RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma
Variables | DMFS | OS | ||
|---|---|---|---|---|
HR(95%CI) | p | HR(95%CI) | p | |
Sex | 0.231 | 0.267 | ||
Male vs Female | 0.52 (0.17–1.52) | 0.49 (0.14–1.72) | ||
Age at diagnosis | 0.214 | 0.025* | ||
≤ 50 vs > 50 | 1.65 (0.75–3.65) | 2.97 (1.15–7.72) | ||
T classification | 0.375 | 0.312 | ||
T1–2 vs T3–4 | 0.56 (0.16–2.00) | 0.43 (0.09–2.19) | ||
N classification | 0.744 | 0.374 | ||
N0–1 vs N2–3 | 0.84 (0.29–2.41) | 0.55 (0.15–2.05) | ||
AJCC stage | 0.195 | 0.269 | ||
I-II vs III-IV | 3.06 (0.56–16.65) | 3.09 (0.42–22.77) | ||
Chemotherapy | 0.300 | 0.519 | ||
No vs Yes | 2.25 (0.49–18.36) | 1.55 (0.41–5.84) | ||
RNF38 status | 0.042* | 0.010* | ||
negative vs positive | 0.43 (0.16–0.97) | 0.19 (0.06–0.67) | ||