Fig. 5
From: RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma
RNF38 inhibits activation of the NF-𝛋B and ERK1/2 signaling pathways. A Levels of p-p65, p-ERK1/2, MMP2 and MMP9 in RNF38-upregulated SUNE-1 and CNE-2 cells and in RNF38-downregulated 6-10B cells. A Levels of 𝛃-catenin in RNF38-upregulated SUNE-1 and CNE-2 cells. C Diagram of the identification processes of RNF38-interacting proteins. D Significant proteins enriched by CNE-2-RNF38 (n = 24) and SUNE-1-RNF38 (n = 41)