Clinical significance and correlation of PD-L1, B7-H3, B7-H4, and TILs in pancreatic cancer

BMC Cancer

Table 1 Association between B7 molecules expression and clinic-pathological parameters in PaCa

Parameters		n	PD-L1		χ² value	P value	B7-H3		χ² value	P value	B7-H4		χ² value	P value
Parameters		n	low	high	χ² value	P value	low	high	χ² value	P value	low	high	χ² value	P value
Age	Female	34	21	13	0.378	0.539	22	12	0.063	0.801	26	8	0.001	0.977
Age	Male	42	23	19			26	16			32	10
Gender	≤60	28	15	13	0.527	0.468	16	12	0.603	0.437	22	6	0.204	0.652
Gender	> 60	50	31	19			33	17			37	13
Differentiation^a	Well	52	35	17	4.478	0.034	37	15	4.638	0.031	41	11	0.870	0.351
Differentiation^a	Poor	26	11	15			12	14			18	8
T stage	≤3 cm	35	18	17	1.494	0.222	20	15	0.876	0.349	27	8	0.078	0.780
T stage	> 3 cm	43	28	15			29	14			32	11
N stage	N0	49	32	17	1.576	0.209	29	20	2.857	0.091	39	10	0.198	0.656
N stage	N1	24	12	12			19	5			18	6
M stage^b	M0	71	42	29	/	1.000	45	26	0.106	0.745	54	17	/	1.000
M stage^b	M1	7	4	3			4	3			5	2
Clinical stage	1	42	27	15	0.731	0.393	27	15	0.003	0.954	34	8	0.713	0.398
Clinical stage	2–4	33	18	15			21	12			24	9

^a Well differentiation: Grade I, II and I-II; Poor differentiation: Grade II-III, III
^b Checked by the modified chi-square test due to the cases less than 5

ISSN: 1471-2407