Table 2 Relationship of GNRI with patient characteristics based on OS and DSS
| Â | Â | Based on OS (cutoff, 97.0) | Based on DSS (cutoff, 95.8) | ||||
|---|---|---|---|---|---|---|---|
All (n = 497) | GNRIHigh (n = 269) | GNRILow (n = 228) | p value | GNRIHigh (n = 289) | GNRILow (n = 208) | p value | |
Age (years) | 80.6 ± 4.0 | 79.7 ± 3.6 | 81.7 ± 4.2 | < 0.001 | 79.8 ± 3.6 | 81.7 ± 4.2 | < 0.001 |
Sex | Â | Â | Â | 0.048 | Â | Â | 0.071 |
 Male | 325 (65.4) | 189 (70.3) | 141 (61.8) |  | 196 (67.8) | 129 (62.0) |  |
 Female | 164 (34.6) | 80 (29.7) | 87 (38.2) |  | 85 (32.2) | 79 (48.0) |  |
BMI | 22.2 ± 3.3 | 23.2 ± 2.7 | 21.0 ± 3.5 | < 0.001 | 23.1 ± 2.7 | 20.9 ± 3.5 | < 0.001 |
Albumin | 3.82 ± 0.54 | 4.18 ± 0.25 | 3.38 ± 0.47 | < 0.001 | 4.16 ± 0.26 | 3.34 ± 0.47 | < 0.001 |
Comorbidity | |||||||
 Cardiac disease | 15 (3.0) | 8 (3.0) | 7 (3.1) | 0.950 | 10 (3.5) | 5 (2.4) | 0.497 |
 Pulmonary disease | 27 (5.4) | 9 (3.3) | 18 (7.9) | 0.026 | 12 (4.2) | 15 (7.2) | 0.138 |
 Diabetes mellitus | 89 (17.9) | 56 (20.8) | 33 (14.5) | 0.066 | 58 (20.1) | 31 (14.9) | 0.138 |
ASA-PS score | Â | Â | Â | 0.002 | Â | Â | 0.002 |
 1 | 42 (8.4) | 23 (8.6) | 19 (8.3) |  | 25 (8.7) | 17 (8.2) |  |
 2 | 366 (73.6) | 213 (79.2) | 153 (67.1) |  | 227 (78.5) | 139 (66.8) |  |
 3 | 89 (18.0) | 33 (12.2) | 56 (24.6) |  | 37 (12.8) | 52 (25.0) |  |
Depth of tumor invasion |  |  |  | < 0.001 |  |  | < 0.001 |
 T1 | 268 (53.9) | 177 (65.8) | 91 (39.9) |  | 189 (65.4) | 79 (38.0) |  |
 T2 | 73 (14.7) | 31 (11.5) | 42 (18.4) |  | 32 (11.1) | 41 (19.7) |  |
 T3 | 104 (20.9) | 40 (14.9) | 64 (28.1) |  | 45 (15.6) | 59 (28.4) |  |
 T4 | 52 (10.5) | 21 (7.8) | 31 (13.6) |  | 23 (7.9) | 29 (13.9) |  |
Lymph node metastasis |  |  |  | < 0.001 |  |  | < 0.001 |
 Present | 161 (32.4) | 68 (25.3) | 93 (40.8) |  | 75 (26.0) | 86 (41.3) |  |
 Absent | 336 (67.6) | 201 (74.7) | 135 (59.2) |  | 214 (74.0) | 122 (58.7) |  |
Histology | Â | Â | Â | 0.670 | Â | Â | 0.464 |
 Differentiated | 334 (67.2) | 183 (68.0) | 151 (66.2) |  | 198 (68.5) | 136 (65.4) |  |
 Undifferentiated | 163 (32.8) | 86 (32.0) | 77 (33.8) |  | 91 (31.5) | 72 (34.6) |  |
Lymphatic invasion | Â | Â | Â | 0.012 | Â | Â | 0.004 |
 Present | 295 (59.4) | 146 (54.3) | 149 (65.4) |  | 156 (54.0) | 139 (66.8) |  |
 Absent | 202 (40.6) | 123 (45.7) | 79 (34.6) |  | 133 (46.0) | 69 (33.2) |  |
Venous invasion | Â | Â | Â | 0.115 | Â | Â | 0.062 |
 Present | 236 (47.5) | 119 (44.2) | 117 (51.3) |  | 127 (43.9) | 109 (52.4) |  |
 Absent | 261 (52.5) | 150 (55.8) | 111 (48.7) |  | 162 (56.1) | 99 (47.6) |  |
pStage |  |  |  | < 0.001 |  |  | < 0.001 |
 I | 296 (59.6) | 190 (70.6) | 106 (46.5) |  | 202 (69.9) | 94 (45.2) |  |
 II | 123 (24.7) | 47 (17.5) | 76 (33.3) |  | 53 (18.3) | 70 (33.7) |  |
 III | 78 (15.7) | 32 (11.9) | 46 (20.2) |  | 34 (11.8) | 44 (21.1) |  |