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Table 3 Correlation between KDM3A IHC score and the clinicopathologic parameters of patients with OS

From: KDM3A-mediated SP1 activates PFKFB4 transcription to promote aerobic glycolysis in osteosarcoma and augment tumor development

Parameters

KDM3A IHC score

P value

High (n = 20)

Low (n = 22)

Sex

Male (n = 27)

12

15

 

Female (n = 15)

8

7

0.7488

Age (year)

< 20 (n = 31)

17

14

0.1658

≥20 (n = 11)

3

8

Tumor size (cm)

< 5 (n = 19)

4

15

**0.0023

≥5 (n = 23)

16

7

Location

Upper limb bone (n = 17)

10

7

0.3462

Lower limb bone (n = 25)

10

15

Lymph node metastasis

Positive (n = 28)

17

11

*0.0232

Negative (n = 14)

3

11

AJCC/TNM stage

I ~ II (n = 12)

2

10

*0.0167

III ~ IV (n = 30)

18

12

  1. KDM3A Lysine-specific histone demethylase 3A, IHC Immunohistochemistry, OS Osteosarcoma, AJCC/TNM American Joint Committee on Cancer/Tumor node metastasis; *p < 0.05; **p < 0.01