Table 4 Gender based genotype frequencies comparison of CTLA4 + 49A/G and IL4 -590C/T polymorphism in HCV induced HCC patients and Control groups
From: Association of CTLA-4 and IL-4 polymorphisms in viral induced liver cancer
Gene | Gender based genotypes | HCV induced HCC % | Control % | Oddsratio | 95% CI-odds ratio | Relativerisk | 95% CI- relative risk | P value |
|---|---|---|---|---|---|---|---|---|
Present | Present | |||||||
CTLA4 |  Male AG | 28.50% | 18.65% | 4.46 | 2.43—8.26 | 2.11 | 1.66–2.87 |  < 0.0001 |
 Male GG | 18.65% | 28.50% | 0.22 | 0.12—0.41 | 0.47 | 0.34 -0.63 |  < 0.0001 | |
 Female AG | 33.62% | 18.30% | 5.32 | 3.06—9.35 | 2.16 | 1.66—2.85 |  < 0.0001 | |
 Female GG | 35.25% | 64.75% | 0.18 | 0.11—0.33 | 0.46 | 0.35 -0.60 |  < 0.0001 | |
IL4 |  Male CC | 32.64% | 16.06% | 5.15 | 2.80 -9.56 | 2.37 | 1.70—3.37 |  < 0.0001 |
 Male CT | 9.84% | 31.61% | 0.17 | 0.09—0.34 | 0.37 | 0.24—0.55 |  < 0.0001 | |
 Male TT | 4.66% | 5.18% | 1.01 | 0.41—2.70 | 1.01 | 0.56 -1.51 |  > 0.99 | |
 Female CC | 31.91% | 12.34% | 4.62 | 2.68—8.04 | 2.01 | 1.56—2.62 |  < 0.0001 | |
 Female CT | 11.49% | 31.91% | 0.14 | 0.083 -0.25 | 0.37 | 0.26—0.51 |  < 0.0001 | |
 Female TT | 8.51% | 3.83% | 2.26 | 0.99—5.42 | 1.39 | 1.00—1.77 | 0.07 |