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Fig. 2 | BMC Cancer

Fig. 2

From: SCARA3 inhibits cell proliferation and EMT through AKT signaling pathway in lung cancer

Fig. 2

SCARA3 inhibits the growth of lung cancer. A Co-expression heat map of SCARA3 with Ki-67 in TCGA-LUAD (n = 706) derived from the UCSC Xena browser. B Cell proliferation was determined with an EZ-Cytox assay using H1299 and A549 cells at time points of 24, 48, and 72 h. Data are presented as mean ± SD of three independent experiments. ***, P < 0.001; **, P < 0.01. C Tumor sphere diameters in ultralow attachment plates were analyzed utilizing H1299 and A549 cells. Sphere formation was imaged on 12 d. Scale bars = 100 μm. Data are presented as mean ± SD of three independent experiments. *, P < 0.05; **, P < 0.01

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