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Fig. 1 | BMC Cancer

Fig. 1

From: Overexpression of angiogenic factors and matrix metalloproteinases in the saliva of oral squamous cell carcinoma patients: potential non-invasive diagnostic and therapeutic biomarkers

Fig. 1

Histology and IHC analysis of angiogenic markers in OSCC tissues and ANT. (A) H&E-stained histological as well as CD31 and CK18 IHC images of human OSCC tissue and ANT sections. (B) Quantitative analysis of MVD in the CD31-stained area. (C) CK18 positive area in ANT and OSCC tissue (n = 5). Relative mRNA expression of (D) CD31, (E) CK18, (F) angiogenin, (G) ANG-2, (H) HGF, (I) PIGF, (J), VEGF, (K) PDGF-BB, (L) bFGF, (M) HB-EGF, and (N) leptin in ANT and OSCC tissue. Data are presented as mean ± SD, n = 10. Significant differences compared to the ANT group, *p < 0.05 and **p < 0.01

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