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Table 3 Univariate and multivariate analyses of prognostic variables for post-recurrence cancer-specific survival in females

From: Clinical impact of primary tumor sidedness and sex on unresectable post-recurrence survival in resected pathological stage II-III colorectal cancers: a nationwide multicenter retrospective study

 

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Primary tumor location

Left vs. Right

1.54

1.19–1.98

0.0009

1.50

1.16–1.94

0.0019

Age (years)

<  75 vs. ≥ 75

0.40

0.83–1.60

0.3970

   

Depth of invasion

T1–3 vs. T4

1.60

1.23–2.07

0.0004

1.61

1.24–2.09

0.0004

Regional lymph node metastasis

Absent vs. Present

1.38

1.02–1.87

0.0342

1.38

1.02–1.87

0.0366

Histopathological type

Differentiated vs. Others

1.16

0.74–1.84

0.5155

   

Recurrence of liver only

Absent vs. Present

1.64

1.22–2.19

0.0009

1.57

1.16–2.13

0.0036

Recurrence of lung only

Absent vs. Present

0.88

0.67–1.15

0.3463

   

Recurrence of peritoneal dissemination only

Absent vs. Present

1.32

0.94–1.86

0.1099

   

Recurrence of extra-regional lymph node only

Absent vs. Present

0.86

0.62–1.18

0.3453

   

Recurrence of bone only

Absent vs. Present

0.50

0.07–3.55

0.4854

   

Recurrence of locoregional only

Absent vs. Present

0.70

0.44–1.12

0.1392

   

Recurrence of anastomosis only

Absent vs. Present

0.88

0.22–3.57

0.8632

   

Number of recurrent organs

Single vs Multiple

1.15

0.57–2.33

0.6940

   

Relapse-free interval (years)

≥ 1.0 vs. <  1.0

1.32

1.02–1.70

0.0354

1.16

0.89–1.51

0.2699

  1. HR Hazard ratio, CI Confidential interval