Table 2 Univariate and multivariate analyses of prognostic variables for post-recurrence cancer-specific survival in males

Primary tumor location

Left vs. Right

1.72

1.41–2.11

< 0.0001

1.31–1.80

< 0.0001

Age (years)

<  75 vs. ≥ 75

1.49

1.10–1.81

0.0076

0.98–1.46

0.0853

Depth of invasion

T1–3 vs. T4

1.08

0.86–1.33

0.4806

Regional lymph node metastasis

Absent vs. Present

1.44

1.16–1.81

0.0012

1.23–1.76

< 0.0001

Histopathological type

Differentiated vs. Others

1.41

1.09–1.84

0.0100

1.18–2.03

0.0014

Recurrence of liver only

Absent vs. Present

1.36

1.14–1.61

0.0005

1.09–1.63

0.0059

Recurrence of lung only

Absent vs. Present

1.25

1.05–1.49

0.0111

0.79–1.17

0.6682

Recurrence of peritoneal dissemination only

Absent vs. Present

1.55

1.24–1.93

0.0001

1.19–1.94

0.0007

Recurrence of extra-regional lymph node only

Absent vs. Present

0.85

0.69–1.05

0.1409

Recurrence of bone only

Absent vs. Present

1.15

0.70–1.88

0.5920

Recurrence of locoregional only

Absent vs. Present

0.80

0.62–1.03

0.0786

Recurrence of anastomosis only

Absent vs. Present

0.97

0.46–2.05

0.9448

Number of recurrent organs

Single vs Multiple

1.38

0.97–1.96

0.0716

Relapse-free interval (years)

≥ 1.0 vs. <  1.0

1.42

1.21–1.66

< 0.0001

1.10–1.54

0.0019