Table 1 Clinicopathological features according to sex

Age (years)

(mean ± SD)

64.9 ± 11.1

65.7 ± 11.2

64.0 ± 10.6

0.0670

66.7 ± 11.0

64.1 ± 11.6

0.0277

Depth of invasion

T1-T3

570 (59.1%)

122 (54.9%)

256 (67.2%)

0.0028

77 (46.1%)

115 (59.3%)

0.0123

T4

394 (40.9%)

100 (45.1%)

125 (32.8%)

90 (53.9%)

79 (40.7%)

Lymph node metastasis

Absent

278 (28.8%)

69 (31.1%)

119 (31.2%)

0.9689

41 (24.6%)

49 (25.3%)

0.877

Present

686 (71.2%)

153 (68.9%)

262 (68.8%)

126 (75.4%)

145 (74.7%)

Adjuvant therapy

Absent

379 (39.3%)

91 (41.0%)

154 (40.4%)

0.6138

64 (38.3%)

70 (36.1%)

0.8811

Present

561 (58.2%)

126 (56.8%)

213 (55.9%)

101 (60.5%)

121 (62.4%)

Unknown

24 (2.5%)

5 (2.2%)

14 (3.7%)

2 (1.2%)

3 (1.6%)

Histopathological type

Differentiated

875 (90.8%)

197 (88.7%)

346 (90.8%)

0.4151

149 (89.2%)

183 (94.3%)

0.0749

Others

89 (9.2%)

25 (11.3%)

35 (9.2%)

18 (10.8%)

11 (5.7%)

Recurrence-free interval (years)

(mean ± SD)

1.41 ± 1.25

1.36 ± 1.25

1.51 ± 1.39

0.1873

1.29 ± 1.13

1.41 ± 1.06

0.3251

 Liver

Present

240 (24.9%)

64 (30.0%)

100 (27.3%)

0.4717

40 (25.2%)

36 (19.3%)

0.1867

 Lung

Present

267 (27.7%)

54 (25.4%)

104 (28.3%)

0.4347

36 (22.6%)

73 (39.0%)

0.0010

 Peritoneal dissemination

Present

123 (12.8%)

40 (18.8%)

29 (7.9%)

0.0001

36 (22.6%)

18 (9.6%)

0.0009

 Extra-regional lymph node

Present

140 (14.5%)

26 (12.2%)

50 (13.6%)

0.6243

27 (17.0%)

37 (19.8%)

0.5022

 Locoregional

Present

120 (12.4%)

20 (9.4%)

68 (18.5%)

0.0023

15 (9.4%)

17 (9.1%)

0.9126

 Anastomotic sight

Present

8 (0.8%)

1 (0.5%)

5 (1.3%)

0.2746

1 (0.6%)

1 (0.5%)

0.9085

 Bone

Present

19 (2.0%)

3 (1.4%)

12 (3.3%)

0.1542

0

4 (2.1%)

0.0259

 Multiple organs

Present

44 (4.6%)

12 (5.4%)

17 (4.7%)

0.6042

8 (4.8%)

7 (3.6%)

0.5753