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Fig. 5 | BMC Cancer

Fig. 5

From: miR-107 is involved in the regulation of NEDD9-mediated invasion and metastasis in breast cancer

Fig. 5

MiR-107 ipromotes the migration, invasion and proliferation of MCF-7 cells. a The scratch test was used to assess the migration ability of stably transfected lines with miR-107 overexpression and miR-107 silencing as well as of empty vector-transfected cells. Scale bar = 100 μm. b Transwell assays were used to assess the migration ability of cells with miR-107 overexpression and miR-107 silencing as well as of empty vector-transfected MCF-7 cells. Scale bar = 100 μm. c The colony formation assay was used to evaluate the proliferation ability of stably transfected cells with miR-107 overexpression and miR-107 silencing as well as cells transfected with empty vector. ***p < 0.001, **p < 0.01, *p < 0.05. d Statistical analysis of the wound closure ability (n = 6). e Statistical analysis of the migration ability of cells (n = 6). F Statistical analysis of the proliferation ability of cells (n = 6)

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