Fig. 2

HRD score evaluation in Cohort I and the score comparison between the Pair and Single Model. A The HRD scores evaluated by the Pair Model of Cohort I are shown and grouped based on BRCA status (deficient vs. non-deficient: intact + monoallelic pathogenic). The dash line (HRD = 38) represents the threshold of positive-HRD that accounts for over 95% (61/64) of the BRCA-deficient samples. B The HRD scores evaluated by Pair and Single Model of each sample are shown on the x- and y-axis, respectively in the dot plot. Positive and negative HRD status using HRD ≥ 38 as the cutoff (dash lines) are labeled by green triangles and red circles, respectively, according to Pair Model evaluation